劉正言，男，江蘇省徐州人。主任醫(yī)師，副教授，復(fù)旦大學(xué)醫(yī)學(xué)博士，美國加州大學(xué)（UCSF）博士后，多次進(jìn)修和培訓(xùn)。學(xué)術(shù)交流：Society for Neuroscience. 2003. New Orleans, USA.；Society for Neuroscience. 2004. San Diego, USA.；AANS. 2004. San Francisco, USA.；International Society for Cerebral Blood Flow and Metabolism. 2005. Amstadam, Netherlands.International Neurosurgery Education and Research, 2009. Florida, USA多次參加國外培訓(xùn)、進(jìn)修、國內(nèi)舉辦的學(xué)術(shù)活動和學(xué)術(shù)交流。?！　≈簠⒕幒头g專著10余部，如：《現(xiàn)代神經(jīng)外科學(xué)》、《實用外科學(xué)》、《實用神經(jīng)病學(xué)》、《現(xiàn)代腫瘤學(xué)》、《核心神經(jīng)系統(tǒng)腫瘤》等 。承擔(dān)科研項目：2007-2011：十一五科技支撐計劃重大項目---腦卒中外科綜合治療技術(shù)體系研究。1998.9－2001.12承擔(dān)上海市醫(yī)學(xué)發(fā)展核心課題：“去骨瓣減壓術(shù)對局灶性腦缺血的保護(hù)機(jī)制及其前瞻性臨床研究”。完成并通過鑒定。2003.3－2005.7在美國加州大學(xué)舊金山分校進(jìn)修時主要從事腦缺血后內(nèi)源性神經(jīng)再生與功能重建的研究，如：炎癥反應(yīng)與神經(jīng)再生；優(yōu)越環(huán)境（EE）對腦缺血和放射治療后神經(jīng)再生的影響；EMX1基因?qū)ι窠?jīng)再生的影響；低血糖對神經(jīng)再生的影響等多項課題。均已完成并發(fā)表多篇SCI文章。2006.1－2008.1承擔(dān)華山醫(yī)院科研課題“抗凋亡治療對延長缺血誘導(dǎo)的內(nèi)源性神經(jīng)干細(xì)胞生存的研究”。目前已完成。2006.1起作為主要負(fù)責(zé)人之一承擔(dān)“蒂清治療腦膠質(zhì)瘤與轉(zhuǎn)移瘤前瞻、通達(dá)、對照臨床研究”。目前正在研究中。發(fā)表論文及會議論文摘要：Chengyu Xia, Zhengyan Liu?, Rong Zhang, Ying Mao, Yin Wan. Primary intrinsic optic chiasm germinoma. Journal of Clinical Neuroscience 18 (2011) 860–862.(通訊作者）劉正言，潘力。顱咽管瘤的治療。國外醫(yī)學(xué)神經(jīng)病學(xué)神經(jīng)外科分冊，1998，25(3)： 132～135劉正言，潘力，王濱江，王恩敏，張南，楊立群。伽瑪?shù)逗土Ⅲw定向32P囊內(nèi)放療聯(lián)合治療顱咽管瘤。臨床神經(jīng)科學(xué)，1998，6(2)： 86～89劉正言，周良輔。去骨瓣減壓術(shù)治療大面積腦梗死的現(xiàn)狀和進(jìn)展。神經(jīng)精神疾病雜志，2000，26(3)： 190～191劉正言，周良輔，黃峰平，毛穎。去骨瓣減壓術(shù)治療大面積腦梗死前瞻性臨床研究方案及初步臨床報道。臨床神經(jīng)科學(xué)，2001，9(1)：5劉正言，周良輔，黃峰平，毛穎。去骨減壓對大鼠局灶性腦缺血保護(hù)作用的有效時間窗。臨床神經(jīng)科學(xué)，2001，9(2)：162～165劉正言，周良輔，毛穎，黃峰平。去骨減壓對大鼠局灶性腦缺血細(xì)胞凋亡的影響。臨床神經(jīng)科學(xué)，2003，11(1)：37～41劉正言，周良輔，任惠民，毛穎，黃峰平。去骨瓣減壓術(shù)對大鼠局灶性腦缺血后腦水腫、血腦屏障、腦血流變化的影響。臨床神經(jīng)科學(xué)，2006，14(1)：72～76董建平 劉正言 羅志偉 董慶漢 董輝。經(jīng)額部小切口—鼻內(nèi)鏡額隱窩開窗聯(lián)合入路治療開顱術(shù)后額竇膿腫。臨床神經(jīng)科學(xué)，2006，14(5)：512劉正言 周良輔 毛穎 黃峰平 丁玎。去骨瓣減壓術(shù)治療大面積腦梗死的短期評價。臨床神經(jīng)科學(xué)，2007，15(1)：59～63Zhengyan Liu, Yang Fan, Seok Joon Won, Melanie Neumann, Dezhi Hu, Liangfu Zhou, Philip R. Weinstein, Jiaing Liu. Chronic Treatment With Minocycline Preserves Adult New Neurons and Reduces Functional Impairment After Focal Cerebral Ischemia. Stroke, 2007,38: 146-152 （SCI, 影響因子 5.855）Yang Fan, Zhengyan Liu*, Philip R. Weinstein, John R. Fike, Jialing Liu. Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation. European Journal of Neuroscience, 2007, 25: 38-46 （SCI, 并列作者，影響因子3.949）Shwuhuey M Hong, Zhengyan Liu*, Yang Fan, Melanie Neumann, Seok Joon Won, Diana Lac, Xuanmin Lum, Philip R. Weinstein, Jialing Liu. Reduced hippocampal neurogenesis and skill reaching performance in Emx1 mutant mice. Experimental Neurology, 2007, 206(1):24-32. （SCI, 并列作者，影響因子 3.767）Jacob Raber, Yang Fan, Yasuhiko Matsumori, Zhengyan Liu, Philip R. Weinstein, John R. Fike, Jialing Liu. Irradiation attenuates neurogenesis and exacerbates ischemia-induced deficits. Ann Neurol, 2004, 55(3): 381-389 （SCI, 影響因子 7.571）Suh SW, Fan Y, Hong SM, Liu Z, Matsumori Y, Weinstein PR, Swanson RA, Liu J. Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus. Diabetes, 2005, 54(2):500-9 （SCI, 影響因子 8.028）Z. Liu, Y. Fan, Y. Matsumori, P.R. Weinstein, J. Liu . Cerebral global ischemia induces neurogenesis but does not increase the total granule cell population in the dentate gyrus of gerbils. Society for Neuroscience. 2003.Z. Liu, Y. Fan, Y. Matsumori, S. Hong, PR. Weinstein, J. Liu. Enriched environment enhances progenitor cell proliferation and survival of newborn cells in the dentate gyrus following transient cerebral global ischemia. Society for Neuroscience. 2004.Z. Liu, Y. Fan, Y. S. Hong, PR. Weinstein, L. Zhou, J. Liu. Minocycline restores neurogenesis and improves functional recovery after stroke injury: different efficacy of early and delayed administration. International Society for Cerebral Blood Flow and Metabolism. 2005.Y. Fan, Z. Liu, Y. Matsumori, P.R. Weinstein, J.R. Fike, J. Liu. Low Does of Irradiation Reduces Neurogenesis but not total granule Cell Population in the Dentate Gyrus of Adult Gerbils. Society for Neuroscience. 2003 Abstract.J. Liu, Y. Fan, Z Liu, T. Kayama, P.R. Weinstein, C. Hsu, Y. Matsumori. Temporal dynamic changes in neurogenesis and newborn cell survival in the dentate gyrus ipsilateral and contralateral to focal ischemic lesion. Society for Neuroscience. 2003 Abstract.Y. Matsumori, Y. Fan, Z. Liu, T. Kayama, A. Sheldon, Z. Vexler, D.M. Ferriero, P.R. Weinstein, J. Liu. HSP70 over-expression protects the neonatal brains from hypoxic/ischemic injury. Society for Neuroscience. 2003 Abstract.Y. Fan, Z. Liu, Y. Matsumori, S. Hong, P.R. Weinstein, J.R. Fike, J. Liu. Environmental enrichment restores the neurogenesis and enhances the survival of newborn cells in the hippocampus of irradiated gerbils. Society for Neuroscience. 2004 Abstract.S. Hong, Y. Matsumori, Y. Fan, Z. Liu, T. Kayama, P.R. Weinstein, C. Hsu, J. Liu. Enriched environment and physical activity enhance the survival of newborn cells in the hippocampus after cerebral focal ischemia in rats. Society for Neuroscience. 2004 Abstract.Y. Matsumori, S. Hong, K. Aoyama, Y. Fan, Z. Liu, T. Kayama, A.R. Sheldon, Z.S. Vexler, D.M. Ferriero, P.R. Weinstein, J. Liu. Increased binding of HSP70 to F is associated with neuroprotection against neonatal hypoxic/ischemic injury in mice with HSP70 over-expression. Society for Neuroscience. 2004 Abstract.